Eight cases of allergy-like food poisoning resulting from the ingestion of
yellowfin tuna, which had been kept in stock for 10 days prior to being coo
ked, are described. The main symptoms were headaches, facial flushing and p
alpitation. Samples of the ingested fish were analyzed for histamine conten
t, and a high level of histamine was confirmed (310 mg/100 g of fish). Cort
icosteroids were given to 3 patients who exhibited dyspnea or persistent sy
mptoms, while the remaining patients improved without medication. In situat
ions where allergy-like clinical features are present after the ingestion o
f food, the possibility of allergy-like food poisoning should be recognized
and included in a differential diagnosis.