Posterior capsule opacification and lens epithelial cell layer formation: Hydroview hydrogel versus AcrySof acrylic intraocular lenses

Purpose. To quantitatively compare the incidence of visually significant po sterior capsule opacification (PCO) and lens epithelial cell (LEC) layer fo rmation on the anterior surface of Hydroview (R) hydrogel and AcrySof (R) a crylic foldable intraocular lenses (IOLs) after implantation. Setting. Single-surgeon ophthalmology practice, Orange Base Hospital, and D udley Private Hospital, Orange, New South Wales, Australia. Methods: This retrospective study comprised 166 eyes of 150 patients (after exclusions) who had cataract extraction and insertion of a foldable IOL in the capsular bag by a single surgeon using a standardized phacoemulsificat ion technique from December 1997 to September 1998. The mean follow-up was 13.1 months (range 6.0 to 23.6 months). The eyes were divided into 2 groups based on the type of IOL implanted: Storz Hydroview H60M (81 eyes) or Alco n AcrySof MA30BA (85 eyes). A neodymium:YAG posterior capsule laser capsulo tomy (PC YAG) was performed for an objective decrease in Snellen best corre cted visual acuity (BCVA) of more than 1 line, significant visual symptoms, or both. This was used as a measure of visually significant PCO. An Nd:YAG anterior surface clearance (ASC YAG) was done for LEC layer formation ante rior to the IOL to better visualize or facilitate treatment of PCO. The rat es of PC YAG and ASC YAG after Hydroview and AcrySof IOL implantation were statistically compared. Results: Forty-five eyes (55.6%) in the Hydroview IOL group and 3 eyes (3.5 %) in the AcrySof IOL group required a PC YAG; the risk difference was 52.0 % (P < .001), An ASC YAG was required in 27 eyes (33.3%) in the Hydroview g roup and 1 eye (1.2%) in the AcrySof group; the risk difference was 32.2% ( P < .001). Survival analysis demonstrated that the only independent predict or of the incidence of PC YAG and ASC YAG over time was IOL type, with the Hydroview IOL group having a statistically significantly higher incidence o f both procedures. Conclusion: There was a greater incidence of visually significant PCO and L EC layer formation on the anterior surface of Hydroview IOLs than of AcrySo f IOLs.