Yh. Hsieh et Sp. Sheu, The effect of density-dependent treatment and behavior change on the dynamics of HIV transmission, J MATH BIOL, 43(1), 2001, pp. 69-80
In this work, we propose a model for heterosexual transmission of HIV/AIDS
in a population of varying size with an intervention program in which treat
ment and/or behavior change of the infecteds occur as an increasing functio
n of the density of the infected class in the population. This assumption h
as socio-economic implications which is important for public health conside
rations since density-dependent treatment/behavior change may be more cost-
saving than a program where treatment/behavior change occurs linearly with
respect to the number of infecteds. We will make use of the conservation la
w of total sexual contacts which enables us to reduce the two-sex model to
a simpler one-sex formulation. Analytical results will be given. Unlike a s
imilar model With linear treatment/behavior change in Hsieh (1996) where co
nditions were obtained for the eradication of disease, we will show that de
nsity-dependent treatment/behavior change cannot eradicate the disease if t
he disease is able to persist without any treatment/behavior change. This w
ork demonstrates the need to further understand how treatment/behavior chan
ge occurs in a society with varying population.