Acute respiratory failure caused by leukaemic infiltration of the lung of a dog

A seven-year-old crossbred male dog with a suspected leukaemic condition wa s referred for Investigation and treatment. A bone marrow aspirate revealed an acute myeloid leukaemia. Combination chemotherapy was administered and the dog initially Improved, but IS days after the initiation of therapy its body condition deteriorated and the animal developed acute respiratory dis tress. On postmortem examination, extensive leukaemic pulmonary infiltrates were evident.