S. Heidari et al., Persistence and tissue distribution of DNA in normal and immunodeficient mice inoculated with polyomavirus VP1 pseudocapsid complexes or polyomavirus, J VIROLOGY, 74(24), 2000, pp. 11963-11965
Introduction of DNA into normal and immunodeficient mice, alone or in compl
ex with VP1 pseudocapsids, has been compared to DNA transfer by viral infec
tion. Similar to natural infection and in contrast to plasmid alone, VP1 ps
eudocapsids efficiently introduced DNA, which remained for months in normal
mice and possibly longer in B- and T-cell-deficient mice.