Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain

The axon guidance molecule netrin-1 has been implicated in the midline repu lsion of developing cranial motor axons. We have examined expression patter ns of the netrin receptors UNC5H1 and DCC in embryonic rat hindbrains, in c ombination with labelling of developing motor neurons. We found that UNC5H1 expression colocalised with a number of cranial motor neuron subpopulation s front embryonic day 11 (E11) to E14, while DCC was expressed by motor neu rons at E12. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.