A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop

Authors
Parr, TB
Citation
Tb. Parr, A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop, MED HYPOTH, 56(5), 2001, pp. 610-613
Citations number
23
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
MEDICAL HYPOTHESES
ISSN journal
03069877 → ACNP
Volume
56
Issue
5
Year of publication
2001
Pages
610 - 613
Database
ISI
SICI code
0306-9877(200105)56:5<610:ANTTEN>2.0.ZU;2-C
Abstract
A new technique for controllable elevation of night time growth hormone (GH ) release in adult humans involves a synergy between oral intake of the nat urally occurring compounds acetyl-L-carnitine (500 mg) and L-ornithine (25- 100 mg) taken at night time sleep after a 3 to 4 hour fast. The set point f or normal hypothalamic GH release appears to include a 'whole body' mitocho ndrial State 3 status 'feed back loop' controlled by systemic acetyl-L-carn itine levels. (C) 2001 Harcourt Publishers Ltd.