Comparison of intracytoplasmic sperm injection for inbred and hybrid mice

Authors
Kawase, Y Iwata, T Toyoda, Y Wakayama, T Yanagimachi, R Suzuki, H
Citation
Y. Kawase et al., Comparison of intracytoplasmic sperm injection for inbred and hybrid mice, MOL REPROD, 60(1), 2001, pp. 74-78
Citations number
30
Categorie Soggetti
Cell & Developmental Biology
Journal title
MOLECULAR REPRODUCTION AND DEVELOPMENT
ISSN journal
1040452X → ACNP
Volume
60
Issue
1
Year of publication
2001
Pages
74 - 78
Database
ISI
SICI code
1040-452X(200109)60:1<74:COISIF>2.0.ZU;2-#
Abstract
We compared the results of intracytoplasmic sperm injection (ICSI) that lea ds to full term development of hybrid (B6C3F1 and B6D2F1) and inbred (C57BL /6) mouse embryos. Although fertilization and pre-im plantation development of C57BL/6 eggs were similar to those of F1 hybrid eggs, post-implantation development of the embryos from C57BL/6 females was significantly poorer t han those of the eggs from hybrid females. Reciprocal crosses of C57BL/6 an d B6C3F1 gametes revealed that the low rate of post-implantation developmen t of C57BL/6 embryos was due to oocyte factor(s), rather than the sperm fac tor.