Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17): PPND family. A longitudinal videotape demonstration

Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), characterized by an autosomal dominant inheritance pattern, has recently b een recognized as a distinct entity that can display a confusingly broad cl inical phenotype. The pallido-ponto-nigral degeneration (PPND) variant is t he prototypical example of the parkinsonism-predominant pattern of FTDP-17. A Longitudinal videotape demonstration of the clinical progression of this entity in a single individual, along with brief videotape segments from th ree additional affected individuals, is presented in order to facilitate re cognition of this disorder. (C) 2001 Movement Disorder Society.