A 54-year-old man suffered from serologically proven neurosyphilis with tet
raspastic syndrome and bladder dysfunction. He showed a pronounced psychopa
thy with cognitive decline and attention/concentration deficits. MRI showed
slowly progressive cerebellar and brainstem atrophy, which has rarely been
described over the past decades. During times of higher incidence and prev
alence of neurosyphilis,infratentorial atrophy had been described occasiona
lly, but today this clinical manifestation has been all but forgotten.