False lateralization by subdural electrodes in two patients with temporal lobe epilepsy

The authors present two patients with medically refractory partial seizures who had invasive recordings with stereotactic depth workup. SDE recordings were falsely lateralizing in both of these patients with pathologically pr oven mesial temporal sclerosis. In temporal lobe epilepsy, SEEG electrodes should be considered when presurgical studies are discordant.