Ketotic hyperglycemia and epilepsia partialis continua

Authors
Placidi, F Floris, R Bozzao, A Romigi, A Baviera, ME Tombini, M Izzi, F Sperli, F Marciani, MG
Citation
F. Placidi et al., Ketotic hyperglycemia and epilepsia partialis continua, NEUROLOGY, 57(3), 2001, pp. 534-537
Citations number
9
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
57
Issue
3
Year of publication
2001
Pages
534 - 537
Database
ISI
SICI code
0028-3878(20010814)57:3<534:KHAEPC>2.0.ZU;2-K
Abstract
Epilepsia partialis continua (EPC) may occur during nonketotic hyperglycemi a but has not been described with diabetic ketoacidosis. The authors report a patient with EPC associated with ketotic hyperglycemia. Brain MRI showed two areas of abnormal signal intensity in the left precentral gyrus and in the right cerebellar hemisphere. Hyperglycemia may reduce seizure threshol d because of the increase in gamma -aminobutyric acid metabolism and may tr igger epileptic discharges.