Place and role of new membranes in multiple organ failure: An advance or rumors

Acute renal failure is a clinical syndrome characterized by high mortality. There have been numerous attempts to improve survival in this condition, s uch as the use of drugs, vasoactive medication, biocompatible membranes, hi gh flux, etc. Nevertheless, mortality remains high (1-4). Some promising pr eliminary results in this field have already been published by our team (5, 6). ARF is on the one side mostly a part of MOF and rare independent clinic al event. As has been previously documented, the greater the number of orga n systems involved in MOF the higher the mortality rate. In a randomized pr ospective study we tried to answer whether biocompatibility, or high flux, or both, have any effect on survival of dialysis dependent patients with mu ltiple organ failure.