Ls. Slingsby et al., Use of a new finger-mounted device to compare mechanical nociceptive thresholds in cats given pethidine or no medication after castration, RES VET SCI, 70(3), 2001, pp. 243-246
Mechanical nociceptive thresholds are regularly used to determine the effic
acy of analgesic agents both experimentally and clinically in a variety of
species. The 'pressure of palpation device' (PPD) was developed for use in
cats and is a small battery operated device with a finger-mounted force sen
sing resistor (FSR, Interlink (TM) Electronics, Northumberland. UK). The PP
D was used in a study assessing the analgesic efficacy of pethidine after c
astration in cats. Pethidine was demonstrated to prevent the development of
post-operative scrotal hypersensitivity for up to 2 hours after castration
, whereas cats given no analgesics showed marked hyperalgesia immediately a
fter surgery. Visual Analogue Scale (VAS) pain scores after castration show
ed a similar analgesic effect of pethidine. These results suggest that the
PPD could become a useful research tool to assess the effectiveness of anal
gesic agents in the cat. (C) 2001 Harcourt Publishers Ltd.