Atopic dermatitis is the first atopic symptom. Local treatment makes use of
emollient cream. Oat cream extracts were suspected of causing sensitizatio
n. This study was performed in 202 children with atopic dermatitis. Two sub
groups were analysed: group 1, 105 children who had applied oat cream (Exom
ega(R), Laboratoires Ducray, France) and group 2, 97 children who had never
applied oat cream. Patch tests were positive for Rhealba(R) oat extract (t
otal extract or protein fractions) in five cases (2.4%): three in group 1 a
nd two in group 2. This result is clinically relevant in group 1, with incr
eased eczema after use of Exomega(R). Oat oral food challenge was negative
in three children with an oat-positive skin prick test. There was no statis
tical difference between the two groups concerning age or positivity of oat
tests and the results of other allergologic tests. Relevant oat cream alle
rgy in children with atopic dermatitis concerned 1.4% of cases. These data
suggest that emollient patch tests should be performed in children with ato
pic dermatitis, in order to use or exclude emollient cream. Further studies
are required to evaluate changes in oat sensitization in older children. (
C) 2001 Editions scientifiques et medicales Elsevier SAS.