Stereoselective synthesis of differentially protected anti-alpha,beta-diamino acid derivatives using arylthionitrooxiranes

Authors
Dumez, E Szeki, A Jackson, RFW
Citation
E. Dumez et al., Stereoselective synthesis of differentially protected anti-alpha,beta-diamino acid derivatives using arylthionitrooxiranes, SYNLETT, (8), 2001, pp. 1214-1216
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
8
Year of publication
2001
Pages
1214 - 1216
Database
ISI
SICI code
0936-5214(200108):8<1214:SSODPA>2.0.ZU;2-U
Abstract
Epoxidation of 1-tolylthio-1-nitroalkenes containing an allylic Z- or Fmoc- protected amino group yields the corresponding, vn-epoxides which. although they cannot be isolated. can be trapped with aqueous ammonia to give stere oisomerically pure anti-alpha,beta -diamino acid derivatives.