KF-Al2O3 is an efficient solid support reagent for the acetylation of amines, alcohols, and phenols. Impeding effect of solvent on the reaction rate

Authors
Yadav, VK Babu, KG Mittal, M
Citation
Vk. Yadav et al., KF-Al2O3 is an efficient solid support reagent for the acetylation of amines, alcohols, and phenols. Impeding effect of solvent on the reaction rate, TETRAHEDRON, 57(32), 2001, pp. 7047-7051
Citations number
29
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
32
Year of publication
2001
Pages
7047 - 7051
Database
ISI
SICI code
0040-4020(20010806)57:32<7047:KIAESS>2.0.ZU;2-I
Abstract
KF-Al2O3 brings about rapid acetylation of a range of amines, alcohols, and phenols with Ac2O/AcCl. Aliphatic alcohols are acetylated chemoselectively in the presence of phenols. 1 degrees alcohols react several times faster than 2 degrees alcohols. 3 degrees alcohols do not react. (C) 2001 Elsevier Science Ltd. All rights reserved.