Synthesis and hydrolytic stability of 5 '-aminoacylated oligouridylic acids

Authors
Tetzlaff, CN Richert, C
Citation
Cn. Tetzlaff et C. Richert, Synthesis and hydrolytic stability of 5 '-aminoacylated oligouridylic acids, TETRAHEDR L, 42(33), 2001, pp. 5681-5684
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
33
Year of publication
2001
Pages
5681 - 5684
Database
ISI
SICI code
0040-4039(20010813)42:33<5681:SAHSO5>2.0.ZU;2-G
Abstract
Dimers and trimers Of uridylic acid vith it phenylalanine residue at their 5'-terminus were prepared in Solution Via intermediates Both acid-labile pr otecting groups. A 5'-aminoacylated octanucleotide was prepared on solid Su pport using a phosphoramidate linker and an allyloxycarbonyl-protected phen ylalanine. (C) 2001 Elsevier Science Ltd. All rights reserved.