Economic development leads to changing interactions between humans and thei
r physical and biological environment. Worldwide patterns of human settleme
nt in urban areas have led in developing countries to a rapid growth of meg
a-cities where facilities for housing, drinking-water and sanitation are in
adequate, thus creating opportunities for the transmission of communicable
diseases such as leishmaniasis. Increasing risk factors are malting leishma
niasis a growing public health concern for many countries around the world.
Certain risk factors are new, while others previously known are becoming m
ore significant. While some risk factors are related to a specific eco-epid
emiological entity, others affect all forms of leishmaniasis. Risk factors
are reviewed here entity by entity.