The accuracy of various Doppler parameters of portal circulation in the dia
gnosis of relevant portal hypertension (presence of gastroesophageal varice
s) was prospectively validated. The following parameters were compared in 5
1 patients with chronic liver disease (40 with cirrhosis and 11 with chroni
c hepatitis): portal vein flow velocity and congestion index, hepatic and s
plenic arteries resistance indexes (RI), modified liver vascular index (por
tal flow velocity/hepatic artery RI) and portal hypertension index, a new i
ndex calculated as: [(hepatic artery RI x 0.69) x (splenic artery RI x 0.87
)]/portal vein flow velocity. Highest accuracy was achieved by the splenic
artery RI and the portal hypertension index (both around 75%) at cut-offs,
respectively, of 0.60 and 12 cm/s(-1), which appeared to be, therefore, the
most favorable parameters for the clinical practice. Their use may limit t
he need for endoscopy to search for varices.