Blunt carotid and vertebral arterial injuries are uncommon but have the pot
ential for devastating consequences. The classic presentation is a neurolog
ic deficit unexplained by computed tomographic scan findings. Screening pat
ients based on injury mechanisms and patterns allows the diagnosis and trea
tment of injuries while they are still asymptomatic, potentially improving
neurologic outcomes. The development of a grading scale may help refine tre
atment guidelines. Accessible grade II, III, and V carotid injuries should
be repaired surgically. Anticoagulation should be considered first-line the
rapy for grade I and IV, and inaccessible grade II and III carotid lesions,
and grade I-IV vertebral injuries. Grade V and persistent grade III lesion
s may be best treated employing endovascular techniques.