The effectiveness of Tsu-San-Li (St-36) and Tai-Chung (Li-3) acupoints fortreatment of acute liver damage in rats

Authors
Liu, HJ Hsu, SF Hsieh, CC Ho, TY Hsieh, CL Tsai, CC Lin, JG
Citation
Hj. Liu et al., The effectiveness of Tsu-San-Li (St-36) and Tai-Chung (Li-3) acupoints fortreatment of acute liver damage in rats, AM J CHIN M, 29(2), 2001, pp. 221-226
Citations number
20
Categorie Soggetti
General & Internal Medicine
Journal title
AMERICAN JOURNAL OF CHINESE MEDICINE
ISSN journal
0192415X → ACNP
Volume
29
Issue
2
Year of publication
2001
Pages
221 - 226
Database
ISI
SICI code
0192-415X(2001)29:2<221:TEOT(A>2.0.ZU;2-3
Abstract
This study investigated the effects of acupuncture on carbon tetrachloride (CCl4) induced acute liver injury in male rats (n=36). The experimental gro ups were injected with CCl4 before, during, or after acupuncture therapy. A cupoints similar to the human Tsu-San-Li (St-36) and Tai-Chung (Li-3) were needled bilaterally. Rats treated with CCl4 had higher levels of serum glut amate-oxalate-transaminase (sGOT) and serum glutamate-pyravate-transaminase (sGPT). Comparing the experimental groups, biochemical and pathological pa rameters of liver injury were significantly reduced when rats were acupunct ured after, not before, CCl4-induced hepatotoxicity. Acupuncture at the Tsu -San-Li and Tai-Chung acupoints cannot prevent acute liver injury but may b e effective in treating liver injury induced by carbon tetrachloride in rat s.