OBJECTIVE: Increasing acceptance of the many permutations of gastroesophage
al reflux disease (GERD) has led to diverse study of the disease and its ef
fects. The goal of this study was to estimate medical care costs attributab
le to a defined GERD population over time.
METHODS: A retrospective cohort control design was used All participants we
re identified from the database of a managed care organization serving 300,
000 people in the northeastern United States. The index population (n = 600
) was defined as anyone who obtained medical services during 1997 or 1998.
for any International Classification of Diseases (ninth revision, Clinical
Modification) codes suggestive of GERD, and/or anyone who received at least
one prescription and one refill for antisecretory or GERD medications duri
ng at least two 3-month periods in 1997 or 1998. A matched cohort (n = 600)
without any diagnosis of GERD was randomly selected as a control group. Bo
th populations were observed restrospectively from January 1, 1990 through
December 31, 1998.
RESULTS: The cost of treating GERD averaged around $510 per year, about 15%
of all medical costs for those with GERD. Treating people with GERD was ab
out 2-fold more costly than treating those without GERD, a marginal cost of
$1500 to $2000 per annum.
CONCLUSION: Although GERD is a low-cost disease to treat, the cost of treat
ing people with GERD is subtantially greater than that for a comparable pop
ulation without GERD. Two explanations may account for the large difference
of costs between the study populations. First, the GERD group may be sicke
r than the control group. Disease severity variables and diagnoses associat
ed with GERD were more commonly diagnosed in the GERD group. Second, an add
itional disease that is not treated appropriately increases the cost of tre
atment geometrically for all diseases. (C) 2001 by Am. Coll. of Gastroenter
ology.