Fatal unintentional occupational poisonings by hydrofluoric acid in the US

Background Case reports have identified hydrofluoric acid (HF) as causing f atal work injury, and HF has both local and systemic toxicity. Surveillance for HF-related mortality is problematic because of the lack of unique codi ng for this acid in hospital records and vital statistics. Methods We identified HF-related fatal work injuries investigated by the Oc cupational Safety and Health Administration (OSHA) for 1984-94 from coding of Hazardous Substance 1460 (HF) and requested case investigation files und er the Freedom of Information Act. We attempted to identify HF-related deat hs in the US for the same period through literature case reports, the Consu mer Product Safety Commission, and the American Association of Poison Contr ol Centers (AAPCC). Results For the 11 year period, OSHA investigated nine deaths in eight inci dents which involved HF Four deaths were from skin contact with concentrate d HF, and five deaths involved both skin contact and inhalation of vapor Un safe work practices were factors in all of the deaths. Calcium chloride or gluconate was noted to have been administered to five of the nine victims. Calcium was administered 90 min after exposure to two victims, and more tha n 6 h after exposure to a third. We were able to establish that the regiona l poison control center had been contacted in regard to only one victim. Fo r the period 1984-94, we were able to identify no additional deaths from CP SC reports, one additional death from AAPCC annual reports, and four other deaths from case reports in the medical literature. Conclusions For the period of this study, OSHA records identified the great est number of HF-related fatalities. The limited information in the records suggest that some victims did not receive appropriate medical care, nor wa s the regional poison center contacted regarding care. The full extent of h ealth problems related to HF could be better quantified if usual surveillan ce sources, such as vital records, included unique coding for this acid. (C ) 2001 Wiley-Liss, Inc.