Osteomyelitis can be caused by trauma in horses of any age or may have a he
matogenous origin in foals. Diagnosis of this disease is based on clinical
signs, radiographic changes, and laboratory values of protein and inflammat
ory cells, especially neutrophils. Clinical signs of inflammation may inclu
de edema, joint effusion, fever, and pain. Lameness is a variable clinical
sign depending on the structures involved in the infection. Radiographic ch
anges are usually diagnostic, but the use of advanced imaging modalities, i
f available, may also be of significant value.