Proton MR spectroscopy of craniopharyngiomas

To date, only a few cases of craniopharyngiomas have been studied by magnet ic resonance (NIR) spectroscopy. We report our spectroscopy experiences wit h five patients having surgically proven craniopharyngiomas. Proton MR spec troscopy images were obtained using the single-voxel mode with spin-echo po int resolved spectroscopy. Very prominent peaks centered at 1-1.5 ppm were noted in spectroscopic analysis, which probably corresponded to lipid/chole sterol peaks, correlating with the histological findings revealing high amo unts of cholesterol in the cyst fluids. (C) 2001 Elsevier Science Ltd. All rights reserved.