Infusion of the metabotropic receptor agonist, DCG-IV, into the main olfactory bulb induces olfactory preference learning in rat pups

Authors
Rumsey, JD Darby-King, A Harley, CW McLean, JH
Citation
Jd. Rumsey et al., Infusion of the metabotropic receptor agonist, DCG-IV, into the main olfactory bulb induces olfactory preference learning in rat pups, DEV BRAIN R, 128(2), 2001, pp. 177-179
Citations number
16
Categorie Soggetti
Neurosciences & Behavoir
Journal title
DEVELOPMENTAL BRAIN RESEARCH
ISSN journal
01653806 → ACNP
Volume
128
Issue
2
Year of publication
2001
Pages
177 - 179
Database
ISI
SICI code
0165-3806(20010629)128:2<177:IOTMRA>2.0.ZU;2-F
Abstract
DCG-IV, a type 2 metabotropic glutamate receptor (mGluR2) agonist, was infu sed into the main olfactory bulb of 1-week-old pups exposed to peppermint o dor. A preference for peppermint was demonstrated 24 h later. The data supp ort the proposal that disinhibition at dendrodendritic synapses between gra nule cells and mitral cells is a critical component of olfactory memory for mation in the rat pup olfactory bulb as well as in the accessory olfactory bulb of adult rodents. (C) 2001 Elsevier Science BY All rights reserved.