Roles of homocysteine in cell metabolism - Old and new functions

Authors
Medina, MA Urdiales, JL Amores-Sanchez, MI
Citation
Ma. Medina et al., Roles of homocysteine in cell metabolism - Old and new functions, EUR J BIOCH, 268(14), 2001, pp. 3871-3882
Citations number
136
Categorie Soggetti
Biochemistry & Biophysics
Journal title
EUROPEAN JOURNAL OF BIOCHEMISTRY
ISSN journal
00142956 → ACNP
Volume
268
Issue
14
Year of publication
2001
Pages
3871 - 3882
Database
ISI
SICI code
0014-2956(200107)268:14<3871:ROHICM>2.0.ZU;2-Y
Abstract
Mild hyperhomocysteinemia has been suggested as a new, independent risk fac tor for cardiovascular disease. This fact has produced a new, increased int erest in the study of homocysteine metabolism and its relation to pathogene sis. This emergent area of biomedical research is reviewed here, stressing the biochemical and metabolic basis of the pathogenicity of increased level s of homocysteine.