Telomeres and telomerases: intimations of immortality

Authors
Crocker, J
Citation
J. Crocker, Telomeres and telomerases: intimations of immortality, EUR J GASTR, 13(8), 2001, pp. 889-890
Citations number
9
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
ISSN journal
0954691X → ACNP
Volume
13
Issue
8
Year of publication
2001
Pages
889 - 890
Database
ISI
SICI code
0954-691X(200108)13:8<889:TATIOI>2.0.ZU;2-O
Abstract
There is a constant balance in cancer cells between division and death. The malignant phenotype is associated with a continuing cell cycle or 'immorta lization'. Telomeres, structures that cap the chromosomes, are related to c ell longevity and are regulated by a ribonucleoprotein called telomerase. T his review describes the possible roles of telomeres and telomerase in the malignant process. Eur J Gastroenterol Hepatol 13:889-890 (C) 2001 Lippinco tt Williams & Wilkins.