The development of an oocyte-containing follicle during gonadotrophin-releasing hormone agonist administration

Administration of gonadotrophin-releasing hormone (GnRH) agonist in a 29 ye ar old woman with infertility due to ovulatory dysfunction resulted in the development of several ovarian cysts. After human chorionic gonadotrophin ( HCG) was injected, the cysts were aspirated and one mature oocyte was retri eved. Intracytoplasmic sperm injection (ICSI) was performed and the resulti ng embryo was transferred. A singleton pregnancy was obtained and a healthy baby was born at 36 weeks of gestation. Because GnRH agonist-derived cysts may contain oocytes, we suggest that when the growth of cysts is accompani ed by high concentrations of oestradiol, the administration of HCG may be u seful to achieve oocyte maturation and advance IVF treatment.