Objective: To compare the emotional state during the first 3 days after cor
onary artery surgery of patients who had undergone early versus conventiona
l extubation.
Design: A prospective, randomized, controlled trial.
Setting: University hospital, single center.
Participants: Eligible patients (n = 100) presenting for elective coronary
artery surgery, randomized to an early extubation group or a conventional e
xtubation group.
Interventions: Emotional status was measured by the Hospital Anxiety and De
pression Scale (HAD), the Self Assessment Manikin (SAM), and the Multiple A
ffect Adjective Check List-Revised (MAACL-R). Tests were administered preop
eratively and on the 1st and 3rd days postoperatively.
Measurements and Main Results: Of patients in the conventional extubation g
roup, 30% showed moderate-to-severe depressive symptoms (HAD score > 10) on
day 3 post-operatively compared with 8% of patients in the early extubatio
n group (p = 0.02). There was a clinically insignificant increase in MAACL-
R depression score on the 1st postoperative day within both groups but no o
ther differences within or between groups in SAM or MAACL-R scores.
Conclusion: Early extubation results in fewer patients displaying depressiv
e symptoms on the 3rd postoperative day but appears to have little effect o
n other measurements of emotional status. Anesthetic management during coro
nary artery bypass graft surgery may play an important role in the overall
well-being of the patient by decreasing the incidence of postoperative depr
ession. Copyright (C) 2001 by W.B. Saunders Company.