In vivo confocal microscopy of corneal epithelial ingrowth through a laserin situ keratomileusis flap buttonhole

We report a case of epithelial ingrowth through a buttonhole 6 months after laser in situ keratomileusis. Elevation topography showed irregular astigm atism and an unreliable pachymetric map. In vivo confocal microscopy showed an epithelial basal cell mosaic with prominent borders and distinct nuclei . No corneal nerves were identified in any image. Cells in the anterior str oma possessed bright, reflective nuclei and appeared to form clusters, The interface between the stromal bed and the flap had formation of nests of fi brotic tissue and epithelial cells, J Cataract Refract Surg 2001; 27:1318-1 322 (C) 2001 ASCRS and ESCRS.