Metastases to the salivary glands from distant neoplasms are unusual, with
most reported cases involving the parotid gland. Metastatic deposits in the
submandibular gland are extremely rare with bilateral involvement not prev
iously reported. We present the case of a patient with advanced breast carc
inoma who has had metachronous involvement of both submandibular glands and
review the literature on this subject.