The authors examined severity of dyskinesia in 119 men and 44 women, compar
ing by gender those with late-onset schizophrenia (LOS) versus early-onset
schizophrenia (EOS). Women with LOS and men with EOS had more severe dyskin
esia than men with LOS and women with EOS. Many factors, including the leng
th of neuroleptic treatment, alcohol and smoking history, and menopausal st
atus, may contribute to the severity of dyskinesia in older patients with s
chizophrenia.