Cardiac papillary fibroelastomas are benign tumors that usually arise from
the valvular endocardium. They are clinically important because of their pr
opensity to embolize. We describe, to the best of our knowledge, the first
reported case of a papillary fibroelastoma arising from the left atrial app
endage, giving rise to multiple cerebral embolic events. The tumor was exci
sed surgically, with no further embolic events.