Successful prevention of recurrent ventricular fibrillation by intravenousisoproterenol in a patient with Brugada syndrome

Authors
Tanaka, H Kinoshita, O Uchikawa, S Kasai, H Nakamura, M Izawa, A Yokoseki, O Kitabayashi, H Takahashi, W Yazaki, Y Watanabe, N Imamura, H Kubo, K
Citation
H. Tanaka et al., Successful prevention of recurrent ventricular fibrillation by intravenousisoproterenol in a patient with Brugada syndrome, PACE, 24(8), 2001, pp. 1293-1294
Citations number
4
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
ISSN journal
01478389 → ACNP
Volume
24
Issue
8
Year of publication
2001
Pages
1293 - 1294
Database
ISI
SICI code
0147-8389(200108)24:8<1293:SPORVF>2.0.ZU;2-Q
Abstract
Intravenous administration of isoproterenol restored the ST-segment configu ration to nearly normal in the right precordial leads and completely preven ted spontaneous VF attacks in a patient with Brugada syndrome. The formatio n of a Brugada-type ECG has been attributed to the transmural dispersion of repolarization of the right ventricular epicardium and related to modulati on of the autonomic nervous system. Our case may provide clues to the patho physiological mechanism of this syndrome.