Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis

Authors
Ahmed, M Shikha, HA Sadhu, SK Rahman, MT Datta, BK
Citation
M. Ahmed et al., Analgesic, diuretic, and anti-inflammatory principle from Scoparia dulcis, PHARMAZIE, 56(8), 2001, pp. 657-660
Citations number
15
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
56
Issue
8
Year of publication
2001
Pages
657 - 660
Database
ISI
SICI code
0031-7144(200108)56:8<657:ADAAPF>2.0.ZU;2-Z
Abstract
Scoparinol, a diterpene, isolated from Scoparia dulcis showed significant a nalgesic (p < 0.001) and anti-inflammatory activity (p < 0.01) in animals. A sedative action of scoparinol was demonstrated by a marked potentiation o f pentobarbital-induced sedation with a significant effect on both onset an d duration of sleep (p < 0.05). Measurement of urine volurne after administ ration of scoparinol indicated its significant diuretic action.