H. Lotkova et al., Activation of mitochondrial glycerophosphate cytochrome c reductase in regenerating rat liver by triiodothyronine, PHYSL RES, 50(3), 2001, pp. 333-336
Triiodothyronine administration before partial hepatectomy increased the ac
tivity of mitochondrial glycerophosphate cytochrome c reductase. The enzyme
activity was further activated after partial hepatectomy during the regene
rative process. Our findings showed that: a) the increase of glycerophospha
te cytochrome c reductase induced by triiodothyronine was further potentiat
ed by the regeneration process, b) the high activity of the glycerophosphat
e shuttle was maintained after partial hepatectomy during the period, when
most of the liver tissue had again been recovered.