Our aim was to evaluate any impact of preoperative resting pressure up
on postoperative physiological results in patients undergoing ileal po
uch anal anastomosis. Ninety patients who had undergone manometric stu
dy before and I year after surgery were divided irate two groups deter
mined by a preoperative mean resting pressure of >50 mm Hg or less tha
n or equal to 50 nam Hg. There were significant differences between th
ese two groups concerning preoperative maximum resting pressure (P < 0
.001) and length of the high-pressure zone (P < 0.005). However, such;
La trend was not seen postoperatively. There were no differences betw
een these two groups relative to postoperative mean or maximum resting
pressure maximum squeeze pressure, length oi high-pressure zone, sens
ory threshold, or capacity. The mean resting pressure decreased after
pouch surgery in 82 Her cent of patients with a preoperative mean rest
ing pressure of >50 mm Hg. Conversely, 83 per cent of patients with a
preoperative mean resting pressure of less than or equal to 50 mm Mg e
xperienced an increase in mean resting pressure after pouch surgery. O
nly 4 of 23 patients with a preoperative mean resting pressure of less
than or equal to 50 nun Kg had decreased postoperative mean resting p
ressure, This latter finding has not been previously described, Howeve
r, the mean resting pressure of those four patients more than fully re
covered within 2 to 3 years after surgery, Although preoperative manom
etry may be useful to analyze data and to counsel patients, if should
not be used to deny patients surgery. Moreover, this study has reveale
d that patients with lower resting pressures do not suffer a deleterio
us decrease in resting pressure but actually have improved postoperati
ve mean resting pressure.