Synthesis of nitriles of delta-oxocarboxylic and gamma-nitrocarboxylic acids

Authors
Silin, MA Kelarev, VI Gracheva, OG
Citation
Ma. Silin et al., Synthesis of nitriles of delta-oxocarboxylic and gamma-nitrocarboxylic acids, RUSS J ORG, 37(2), 2001, pp. 210-213
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
37
Issue
2
Year of publication
2001
Pages
210 - 213
Database
ISI
SICI code
1070-4280(200102)37:2<210:SONODA>2.0.ZU;2-6
Abstract
A cyanoethylation of 2-acetyl-5-R-furans, 1-nitro-2(5-R-2-furyl)ethanes, an d 2-nitro-1-(2-furyl)propane was investigated. The optimum conditions were determined for preparation of monocyanoethylated products: nitriles of 5-ox o-5-(5-R-2-furyl)pentanoic and 4-nitro-5-(5-R-2-furyl)pentanoic acids. The cyanoethylation of furyl-containing nitroethanes with excess acrylonitrile provided bisadducts, dinitriles of 4-nitro-4-(5-R-furfuryl)heptanedionic ac ids.