A new and convenient synthesis of 1-aryl-2-dimethylaminoethanols

Authors
Nyerges, M Fejes, I Viranyi, A Groundwater, PW Toke, L
Citation
M. Nyerges et al., A new and convenient synthesis of 1-aryl-2-dimethylaminoethanols, SYNTHESIS-S, (10), 2001, pp. 1479-1482
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
10
Year of publication
2001
Pages
1479 - 1482
Database
ISI
SICI code
0039-7881(200108):10<1479:ANACSO>2.0.ZU;2-K
Abstract
An efficient two-step synthesis of 1-aryl-2-dimethylaminoethanols 4 is desc ribed, consisting of oxazolidine 3 generation from the cycloaddition of an azomethine ylide to an aldehyde, followed by reductive ring-opening.