A concise, stereoselective synthesis of meso-2,6-diaminopimelic acid (DAP)

Authors
Collier, PN Patel, I Taylor, RJK
Citation
Pn. Collier et al., A concise, stereoselective synthesis of meso-2,6-diaminopimelic acid (DAP), TETRAHEDR L, 42(34), 2001, pp. 5953-5954
Citations number
17
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
34
Year of publication
2001
Pages
5953 - 5954
Database
ISI
SICI code
0040-4039(20010820)42:34<5953:ACSSOM>2.0.ZU;2-C
Abstract
The preparation of meso-2,6-diaminopimelic acid 1 is described. The key ste p in the synthesis is Suzuki coupling of the novel organoboron homoalanine equivalent 3 with methyl (2Z)-3-bromo-2-[(tert-butoxycarbonyl)amino]-2-prop enoate 5. (C) 2001 Elsevier Science Ltd. All rights reserved.