The increase in the number of projects carried out in protein crystallograp
hy laboratories has emphasized the need for effective management of project
information and data. To meet this need, a flexible web-accessible databas
e for protein crystallography project management (LISA) has been developed
using the open-source software MySQL and PHP4. The database contains inform
ation about all aspects of structure-determination projects, including prim
er and plasmid sequences, protein expression, purification and crystallizat
ion results, structure coordinate files and resultant publications. The dat
abase web pages include links to relevant servers and contain, in addition,
tools for processing stored information. The software package is freely av
ailable.