S. Sueda et al., Clinical characteristics and possible mechanism of paroxysmal atrial fibrillation induced by intracoronary injection of acetylcholine, AM J CARD, 88(5), 2001, pp. 570
Citations number
14
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
We recently reported on the frequency of provoked coronary artery spasm wit
h intracoronary injection of acetycholine (ACh) and the major complications
of ACh testing in Japanese patients.(1,2) Multicenter studies have address
ed the fact that not only chronic atrial fibrillation (AF), but also paroxy
smal AF could predispose patients to systemic embolism.(3-7) According to C
oumel,(8) disorders of autonomic nervous balance seem to play a major role
of occurrence of paroxysmal AF. Paroxysmal AF often occurred during spasm p
rovocation tests of ACh. However, clinical investigation of ACh-induced par
oxysmal AF in detail has not been reported. Moreover, no data exist concern
ing the correlation between paroxysmal AF during daily life and ACh-induced
paroxysmal AF. In this study, we sought to clarify the clinical characteri
stics and possible mechanism of ACh-induced paroxysmal AF in patients with
coronary arteriography and spasm provocation tests of ACh.