Genetic hemochromatosis is a rare disease entity among French Basques: a center-based study from the General Hospital of Basque Country

Authors
Bauduer, F Scribans, C Renoux, M Borot, N
Citation
F. Bauduer et al., Genetic hemochromatosis is a rare disease entity among French Basques: a center-based study from the General Hospital of Basque Country, ANN HEMATOL, 80(8), 2001, pp. 472-473
Citations number
9
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
ANNALS OF HEMATOLOGY
ISSN journal
09395555 → ACNP
Volume
80
Issue
8
Year of publication
2001
Pages
472 - 473
Database
ISI
SICI code
0939-5555(200108)80:8<472:GHIARD>2.0.ZU;2-W
Abstract
A center-based study from the general hospital of Basque country has been p erformed to evaluate the importance of genetic hemochromatosis among French Basques. A sample of 37 patients from 34 families fulfilling the diagnosis criteria of hemochromatosis was obtained. Only four of them were of Basque origin: two homozygotes for C282Y, one homozygote for H63D, and one hetero zygote for C282Y These results suggest a significant lower prevalence of ge netic hemochromatosis in Basques than in people from other French regions ( P = 0.001). They underline further the biological specificity of this popul ation.