Y. Kikuchi et al., A rare case of advanced ovarian carcinoma who developed difficulty walking25 days after treatment with weekly paclitaxel, ANTI-CANC D, 12(7), 2001, pp. 631-633
Although taxol has shown significant activity in advanced ovarian cancer, p
eripheral neuropathy is likely to become the major dose-limiting toxicity.
We describe a case of advanced ovarian carcinoma who developed difficulty w
alking because of marked pain in the lower extremities and loss of proprioc
eption 25 days after treatment with weekly taxol (80 mg/m(2) x 3). [(C) 200
1 Lippincott Williams & Wilkins.].