Alginate, a copolymer Of beta -D-mannuronic acid and alpha -L-guluronic aci
d and currently commercially produced from the marine brown algae, can also
be biologically produced by bacteria such as Azotobacter vinelandii, A. ch
roococcum and several species of Pseudomonas. The ever-increasing applicati
ons of this polymer in the food and pharmaceutical sectors have led to cont
inuing research interest aimed at better understanding the metabolic pathwa
ys, the physiological or biological function of this polymer, the regulatio
n of its formation and composition, and optimising the microbial production
process. These aspects are reviewed here, with particular attention to alg
inate formation in the soil bacterium A. vinelandii. In addition, the biote
chnological and industrial applications of alginate are summarised.