In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng

Authors
Bae, EA Han, MJ Baek, NI Kim, DH
Citation
Ea. Bae et al., In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng, ARCH PH RES, 24(4), 2001, pp. 297-299
Citations number
14
Categorie Soggetti
Pharmacology & Toxicology
Journal title
ARCHIVES OF PHARMACAL RESEARCH
ISSN journal
02536269 → ACNP
Volume
24
Issue
4
Year of publication
2001
Pages
297 - 299
Database
ISI
SICI code
0253-6269(200108)24:4<297:IVAPAO>2.0.ZU;2-B
Abstract
This study investigated the effect that some polyacetylenes and protopanaxa triol, which were isolated from heated ginseng (family Araliaceae), have on inhibiting Helicobacter pylori (HP) growth. Among the compounds tested, pa naxytriol was quite effective in inhibiting HP growth with an MIC of 50 mug /ml. Ginsenoside Rh1 and protopanaxatriol weakly inhibited H+/K+-ATPase fro m a rat stomach.