Synthesis of d-labeled N-alkylmaleimides and application to quantitative peptide analysis by isotope differential mass spectrometry

Authors
Niwayama, S Kurono, S Matsumoto, H
Citation
S. Niwayama et al., Synthesis of d-labeled N-alkylmaleimides and application to quantitative peptide analysis by isotope differential mass spectrometry, BIOORG MED, 11(17), 2001, pp. 2257-2261
Citations number
16
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
11
Issue
17
Year of publication
2001
Pages
2257 - 2261
Database
ISI
SICI code
0960-894X(20010903)11:17<2257:SODNAA>2.0.ZU;2-3
Abstract
d-Labeled N-alkylmaleimides have been prepared for specific modification of the terminal Sf I groups of cysteine residues in proteins or peptides. The se reagents are useful tools for quantitative analysis of peptides by stabl e isotope differential mass spectrometry. (C) 2001 Elsevier Science Ltd. Al l rights reserved.