Ka. Attia et al., Clinical, endoscopical and histological aspects of Helicobacter pylori in Cote d'Ivoire: study of 102 cases., B S PATH EX, 94(1), 2001, pp. 5-7
Background: Helicobacter pylori (H. pylori) is the most frequent aetiologic
al factor of chronic gastritis (CG). The relationship between H. pylori gas
tritis, gastra-duodenal ulcer and some gastric cancers (adenocarcinoma, gas
tric MALT lymphoma) has now been proven.
Aim: Describe clinical, endoscopical and histological aspects of H. pylori
gastritis in Cote d'Ivoire.
Methods: retrospective analysis of 1960 gastroscopy reports carry out betwe
en January 1994 and December 1995. Analysis of clinical and gastric histolo
gical results in 137 patients.
Findings: Among 137 patients with gastric biopsy, 102 had H. pylori gastrit
is (68 men, 38 women, mean age: 39.3 years) and 35 had chemical gastritis.
Epigastric pain was the most frequent symptom, The mucosa was frequently er
ythematous or exsudative at endoscopy. Histological anomalies were located
in the antrum, the fundus or generalised, respectively in 33.3%, 25.5% and
41.2% of cases. Mild atrophic CG was more frequent in various locations. Ga
stritis activity was present in 81.4%, intestinal metaplasia in 18.6% and f
ollicular lymphoid hyperplasia in 36.3% of cases.
Conclusion: Clinical and endoscopical aspects of H. pylori gastritis did no
t present any particularities. Fundic gastritis without antral localisation
was not unusual. This situation could be the result of antibiotic and gast
ric acid secretion inhibitor treatments.